Prostate enucleation by HoLEP and TUR-P for benign prostatic enlargement

Enucleation of the prostate

Prostate tissue is removed during a minimally invasive surgical procedure. After the procedure, it is no longer necessary to take any medication that was required for emptying the bladder.

At the Goldstadt Private Clinic, in addition to conventional prostate resection (TUR-P), modern prostate enucleation (HoLEP – holmium laser enucleation of the prostate) is used to treat benign prostatic enlargement. These minimally invasive methods enable effective relief of symptoms and a quick recovery.

When should HoLEP or TUR-P be recommended?

If bladder emptying is incomplete due to the size of the prostate and this can no longer be successfully treated with drug therapy, HoLEP or TUR-P is recommended. It is worth mentioning that after the operation, no more medication needs to be taken for bladder emptying. The time at which surgery is indicated must be carefully considered. As a rule, benign prostatic enlargement is treated in the event of complications of bladder emptying (urinary retention, bladder stones, frequent urinary tract infections). However, it should be borne in mind that after HoLEP or TUR-P, the changes in the bladder muscle, which often lead to an increased urge to urinate, only regress slowly, and therefore the procedure should not be delayed for too long. Compared with TUR-P, HoLEP is better suited for pronounced enlargements. Tissue removal is very good.

Holmium laser enucleation (HoLEP) at a glance

Indication Enlargement of the prostate with impaired bladder emptying
Principle minimally invasive operation via the urethra, removal of prostate tissue with the holmium laser
Operating time depending on the size of the prostate, approx. 1–2 hours
Hospital stay 2–3 days
Note Spinal anaesthesia or general anaesthesia

Transurethral prostatectomy (TUR-P) at a glance

Indication Enlargement of the prostate with impaired bladder emptying
Principle minimally invasive operation via the urethra, removal of prostate tissue with an electric loop
Operating time depending on the size of the prostate, approx. 1 hour
Hospital stay 2–3 days
Note Spinal anaesthesia or general anaesthesia

Questions about HoLEP and TUR-P

If bladder emptying is incomplete due to the size of the prostate and this can no longer be successfully treated with drug therapy, HoLEP or TUR-P is recommended. It is worth mentioning that after the operation, no more medication needs to be taken for bladder emptying. The time at which surgery is indicated must be carefully considered. As a rule, benign prostatic enlargement is treated in the event of complications of bladder emptying (urinary retention, bladder stones, frequent urinary tract infections). However, it should be borne in mind that after HoLEP or TUR-P, the changes in the bladder muscle, which often lead to an increased urge to urinate, only regress slowly, and therefore the procedure should not be delayed for too long. Compared with TUR-P, HoLEP is better suited for pronounced enlargements. Tissue removal is very good.

HoLEP is a minimally invasive surgical procedure performed via the urethra. The prostate tissue is detached from the prostate capsule with the holmium laser and pushed into the urinary bladder. There, the removed prostate tissue is morcellated and removed from the bladder. The tissue is examined histologically in order to detect any malignant cells of the prostate. At the end of the operation, a bladder catheter is inserted, which can usually be removed on the 2nd day after the operation. As a rule, patients are discharged from inpatient treatment on the 3rd day after the operation.

TUR-P is a minimally invasive surgical procedure performed via the urethra. The prostate tissue is removed with an electric loop from the inside out to near the prostate capsule. The tissue is examined histologically in order to detect any malignant cells of the prostate. At the end of the operation, a bladder catheter is inserted, which can usually be removed on the 2nd day after the operation. As a rule, patients are discharged from inpatient treatment on the 3rd day after the operation.

In the case of a very large prostate, especially in combination with concomitant conditions such as bladder stones or bladder diverticula, robot-assisted da Vinci enucleation of the prostate or open surgery may also be possible. The question of the best surgical method for benign prostatic enlargement can only be determined on an individual basis in consultation with the patient.

Prostate enucleation can be performed using various procedures such as holmium laser enucleation of the prostate (HoLEP) or transurethral resection of the prostate (TUR-P). At the Goldstadt Private Clinic, the procedure begins with a thorough preliminary examination. The patient is then operated on under general or spinal anaesthesia, and the excess tissue is removed using a laser or resection instrument. After the procedure, the patient is monitored in the clinic to ensure a quick recovery.

Prostate resection or enucleation becomes necessary when patients suffer from a significant impairment of urine flow due to an enlarged prostate. Typical symptoms are frequent urination, urination at night, a weak urine stream and incomplete bladder emptying. The specialists at the Goldstadt Private Clinic assess each case individually and decide together with the patient on the best treatment option.

The terms "enucleation" and "resection" of the prostate refer to two different surgical procedures for the treatment of benign prostatic enlargement.

Enucleation (holmium laser enucleation of the prostate, HoLEP):

In enucleation, excess prostate tissue is removed with a holmium laser. The laser enables precise separation of the tissue, which is then moved into the bladder and aspirated from there. This procedure is characterised by high precision and a low risk of bleeding and is particularly suitable for larger prostate volumes.

Resection (transurethral resection of the prostate, TUR-P):

In resection, the excess prostate tissue is removed with an electric loop that is inserted through the urethra. This method is widespread and is often used for small to medium-sized prostate enlargements. It is known for its effectiveness in relieving symptoms such as urinary retention.

Both methods, enucleation and resection, are performed at the Goldstadt Private Clinic by experienced urologists to ensure optimal treatment for patients.

Find out more about our urology specialists here.

Prostate enucleations and resections at the Goldstadt Private Clinic are performed by experienced urologists. One of the leading experts in this field is Prof. Dr. med. Sven Lahme, specialist in urology and medical director of the Goldstadt Private Clinic. Prof. Dr. Lahme has many years of experience and extensive expertise in the use of state-of-the-art surgical techniques such as holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TUR-P). His expertise and commitment to excellent medical care ensure that patients receive the best possible treatment.

You can find further information about Prof. Dr. med. Sven Lahme here.

At the Goldstadt Private Clinic, two main methods are used for prostate enucleation: holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TUR-P). Both procedures have proven to be effective and offer different advantages depending on the individual needs of the patient.

As with any surgical procedure, there are risks associated with prostate enucleation, but these are minimised by careful planning of the procedure. Possible complications include bleeding, infections, temporary incontinence and sexual dysfunction. Patients are informed in detail about the risks during the informative consultation. The treating urologists take all necessary precautions to minimise them.

Good to know

Prostate cancer can still develop even after the enlarged prostate tissue has been removed. For this reason, the presence of prostate carcinoma is routinely ruled out during the regular follow-up examinations.

Videos on the surgical methods:

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Everything you need to know about HoLEP surgery

This video shows directly in the operating theatre which devices are used in HoLEP and how the technique works.

  • How does HoLEP basically work in the operating theatre?
  • Which instruments are needed – laser, endoscope, morcellator?
  • How is the prostate tissue detached from the capsule?
  • Why is complete enucleation with a laser an advantage over conventional TUR-P?
  • How does morcellation work and what is it for?
  • What do the mandarin and the sausage models show?

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Holmium laser enucleation

In this video, you will learn more about holmium laser enucleation, or HoLEP for short.

  • Purpose: Treatment of an enlarged prostate (benign prostatic hyperplasia) that leads to a weak urine stream, residual urine and a strong urge to urinate.
  • Indication: When drug therapy is not sufficient.
  • Procedure:
    • Endoscopic access via the urethra
    • Prostate tissue is detached from the capsule ("enucleation") – similar to peeling an orange
    • The detached tissue is morcellated and aspirated (morcellator)
  • Result:
    • Urethra clear again, strong urine stream
    • Bladder wall remains thickened → urge to urinate only improves over weeks to months
    • Ejaculation reduced (dry) due to missing prostate tissue
    • Erectile function usually remains unchanged
  • Advantages: Minimally invasive, effective for a greatly enlarged prostate, better control than classic open enucleation.

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TUR-P versus HoLEP

Which prostate operation is the right one?

In this video, Sven Lahme compares transurethral resection of the prostate (TUR-P) with holmium laser enucleation of the prostate (HoLEP).

  • How TUR-P (transurethral resection of the prostate, classic method) works
  • How HoLEP (holmium laser enucleation) works
  • Which of the surgical methods can be recommended?
  • Guidelines vs. modern experience
  • Histological examination & clarification of cancer
  • Summary & clear recommendation

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Benign prostatic enlargement

Surgical methods compared

About 30% of men over 60 suffer from symptoms such as a weak urine stream, residual urine or frequent urination. In this video, Prof. Lahme clearly explains the most important treatment options for benign prostatic enlargement (benign prostatic hyperplasia, BPH) and provides orientation in the jungle of surgical methods.

  • Anatomy & cause of the bladder emptying disorder
  • Residual urine – when does it become dangerous?
  • Explanations of surgical methods
  • How do you find the right method?
  • Overview of guidelines & proven procedures
  • Further information

After the operation:

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Problems urinating after prostate surgery?

This video explains why there is a risk of recurrence with TUR-P and how the narrowing is eliminated by a so-called Y-V plasty as part of a robot-assisted da Vinci operation.

  • What is a prostatic fossa stricture?
  • How does the scarred narrowing develop?
  • Symptoms: how to recognise it
  • Endoscopic treatment of the narrowing
  • Reconstructive Y-V plasty explained
  • Future therapy: drug-coated balloon

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Sexuality after prostate surgery

Will I become impotent?

Many men are worried: what happens to my sexuality after prostate surgery? In this video, Prof. Dr. Sven Lahme uses sketches to explain clearly how different procedures affect libido, erection and ejaculation.

  • Introduction: prostate surgery & sexual function
  • The 4 sexual functions simply explained
  • What remains unchanged? (libido & orgasm)
  • Prostate surgery for enlargement – effects
  • Ejaculation after surgery (dry orgasm)
  • Erection after prostate reduction
  • Prostate removal for cancer explained
  • Risk of erectile loss & the nerves
  • Chances of preserving potency
  • Conclusion: what men can really expect

General information:

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HoLEP

What the stay in a specialist clinic involves

Inpatient treatment for holmium laser enucleation of the prostate (HoLEP)

Holmium laser enucleation of the prostate (HoLEP) is performed for benign prostatic enlargement when symptoms such as a weak urine stream or incomplete bladder emptying are present. You can find more information on this in this video.

  • Procedure: The doctor explains the procedure and risks, and the anaesthetist discusses the choice of anaesthesia (general anaesthesia or spinal anaesthesia). On the day of the operation, the patient is admitted as an inpatient having fasted.
  • Operation and aftercare: Duration about one to two hours. To ensure urine drainage, a bladder catheter with continuous irrigation is inserted, which is removed after about two days.
  • It is then checked whether bladder emptying is working properly again – among other things by means of a urine flow measurement and an ultrasound check.
  • Duration and healing: The inpatient stay is about three days. After discharge, the internal surgical wound usually heals completely within a few weeks.

About this page:

Author

Prof. Dr. med. Sven Lahme
Urology specialist

Medical director of the Goldstadt-Privatklinik.
Specialist for Urology, Mini-PCNL and robot-assisted da Vinci procedures.

Member in Scientific Societies and Reviewer of scientific journals.

Creation Date: 22.07.2024Modification date: 12.12.2025

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